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S5

AI Drug Virtual Screening

Target -> binding pocket -> molecular docking -> candidate molecule

TorchANI neural network potential accuracy approaches DFT. End-to-end virtual screening pipeline.

4-8 weeks300K-1M/projectCapability Coverage 70%

Pipeline Flow

End-to-end dry-computing loop

1
Target Structure
ESMFold prediction or PDB retrieval
2
Binding Pocket
P2Rank predicts druggable binding sites
3
Molecular Docking
AutoDock Vina large-scale virtual docking
4
ADMET Prediction
RDKit + QED evaluate metabolism and toxicity
5
Candidate Ranking
REINVENT AI generation + screening
6
Neural Network Potential Validation
TorchANI accuracy approaches DFT
7
Delivery Report
Candidate molecule SMILES + docking conformation + ADMET scores

Core Tools

ESMFoldP2RankAutoDock VinaRDKitQEDREINVENTTorchANI

Core Advantages

TorchANI

Accuracy approaches DFT but 1000x faster

End-to-end Automation

Target -> pocket -> docking -> ADMET -> ranking

AI Generation + Screening

REINVENT generates novel candidate molecules

Capability Coverage

70%

Start Your Project AI Drug Virtual Screening

Start with just 1 project, no team needed.