Your Needs, Our Computing Backend
Four-layer capability architecture + four user channels. From silicon to information carriers, precisely matched.
Four-Layer Capability Architecture
From silicon to information carriers · four-layer stack
Chip, Hardware & Computing Architecture
BioCompute IC self-developed processor + DiVo Box anti-reverse-engineering packaging + edge inference deployment + cloud-edge collaborative scheduling.
Model Training, Fine-tuning & Deployment
Pairformer Core · 744B->60B distillation · RNALens self-developed fine-tuning · 6-layer anti-reverse-engineering.
Agent Design & Deployment
Pairformer-driven multi-Agent collaboration system · pipeline orchestration · self-developed Agent framework.
Dry-Computing Services
8-step neoantigen pipeline · VCF-Report · pMHC structure prediction · mRNA optimization · genome interpretation report.
Computing Services · 6 Pipelines
Contract-based, per-project delivery
Four User Channels
Precisely matched to your role and needs
B · Biopharma Enterprises
Enterprise computing services · model development · private deployment
Target discovery, drug screening, pipeline customization--enterprise-grade dry-computing services.
A · Research Users
Independent researchers · university labs · research institutes
Publication-grade precision, four-model cross-validation. Unified channel for independent researchers and institutional labs.
C · Health & Wellness Consumers
150 Years Long Life · Live to 150 for the nation
Whole-genome deep interpretation, longevity management, precision medication--pay per service.
G · Government & Public Sector
Public policy analysis · regional projects
Private deployment ensures data never leaves the institution.
Ready-to-Use Dry-Computing Services
Not a vision on a slide--but proven, validated, deliverable engineering capability
Neoantigen mRNA Vaccine 8-Step Pipeline
✓ VerifiedFrom VCF/BAM to mRNA sequence design, fully validated end-to-end. Three differentiators: pMHC 3D structure verification, 5-dimensional immunogenicity scoring, in-house RNALens fine-tuning. TESLA benchmark AUROC=0.698.
pMHC 3D Structure Prediction + Docking Validation
✓ VerifiedTraditional pipelines stop at IC50 values. DiVo Gen²AI uses Protenix to build atom-level pMHC 3D structures for each candidate neoantigen, validated by Protenix-Dock physical docking. 400+ complexes at scale.
Genome Interpretation Report (Bilingual)
✓ VerifiedVCF QC → VEP annotation → ANNOVAR functional annotation → ACMG classification → health report. Bilingual MD/HTML/PDF delivery, 12+ batches validated.
HLA Typing (Dual-Tool Cross-Validation)
✓ VerifiedOptiType + Polysolver dual-algorithm cross-validation, 4-digit resolution HLA-I typing. Provides基础 input for neoantigen pipelines, also independently deliverable.
mRNA Sequence Optimization (RNALens)
✓ VerifiedMRL prediction model fine-tuned in 3 stages on DNABERT-Z 117M — not a third-party API call. CAI 0.7→0.95, 3 tissue-adapted models (HEK/Muscle/PC3).
CAR-T Cell Therapy Computation
✓ VerifiedNeoantigen pipeline + RNA-seq surface antigen mining + de novo Binder design + structure validation. For medical institution partnerships, not direct-to-patient. Xie Qi / Cao Longxing Nature BME路线.
Aesthetic PRS · Genetic Beauty Profile
✓ VerifiedPolygenic risk scores for aesthetic targets — collagen loss, photoaging sensitivity, hair loss risk, pigmentation. PRSice-2+PRS-CS dual engine, Chinese population calibrated. B2B2C model — the tech backbone for aesthetic clinics.
Anti-Aging Peptide & Protein Engineering
✓ VerifiedFinding anti-aging molecules in 3D space — MMPs inhibitors, collagen engineering, Sirtuin activators. 100% tools deployed and validated: Protenix V2 + Pro-Prime + BoltzGen(5-weight complete) + ProteinMPNN + MHCflurry.
Skin Microbiome × Host Gene Joint Mining
✓ VerifiedSkin condition is a symbiotic result of genes and microbiota. 16S/ITS microbiome analysis (DADA2 local + MGnify online fallback) cross-mined with host HLA/FLG immune genes, revealing gene-microbiota-skin phenotype ternary relationships.
Follicle Induction · Five-Factor Combination
◈ ExploratoryFrom repair to regeneration — WNT10B+FGF9+Noggin+RSPO1+SHH-N five-factor combination inducing new follicles on hairless skin. Protenix V2 structure prediction + ProteinMPNN engineering design validated; mRNA delivery design (GEMORNA) ready. ARM mode: design only, no manufacturing.
Cooperation Modes
Flexible selection, combine as needed
Chip & Computing Architecture
Custom design and consulting. BioCompute IC / DiVo Box dedicated solutions, full-stack from chip architecture to edge deployment.
Private Platform Deployment
Turn-key platform + annual tech support subscription. Run independently on your own compute.
Model Training & Fine-tuning
Train dedicated models on customer data, deliver weights and inference pipelines.
Computing Services
Contract-based, per-project delivery. Define computing pipelines and deliver deliverables.
Not just tools--we are your computing backend
Compute · Design · Analysis · Insights