DiVo Bio Agent Platform

L3 · Agent Layer

Agent Design & Deployment
Multi-Agent Collaboration System

Multi-Agent collaboration system · pipeline orchestration · task scheduling · self-developed Agent framework--turning models into executable action units in specific business scenarios

L2 ModelsL3 AgentsL4 Computing

WHY AGENT LAYER

Why Agents Are Needed Above Models

Models answer questions--Agents solve problems. Models are the brain, Agents are the hands and feet

Turn Models into Action Units

Models can only generate text--Agents can call tools, schedule pipelines, chain multi-step computations, turning model capabilities into executable business processes.

Multi-Agent Collaboration

Single models have limited capabilities--Protein Agent, Gene Agent, Tumor Agent each specialize, Orchestration Agent coordinates task decomposition, working like a real bioinformatics team.

Interactive Interpretation

Agents don't just output files--they interpret results, answer follow-ups, recommend next steps. Upgrading "get numbers and judge yourself" to "AI explains meaning and gives advice".

ARCHITECTURE

Four-Layer Architecture

Inter-layer MCP protocol communication--dialog -> collaboration -> tools -> computing

Dialog Interaction Layer

L3 · Layer 1

Natural language -> Agent understands intent -> schedules tools -> generates reports. Continuously understanding context in multi-turn dialog, translating researchers' vague questions into precise computing tasks.

Intent recognitionMulti-turn dialogResult interpretationVisual reports

Multi-Agent Collaboration Layer

L3 · Layer 2

Protein Agent, Gene Agent, Health Agent each handle their domain--Orchestration Agent decomposes tasks, distributes to domain Agents, aggregates results. Collaborating like a real bioinformatics team.

Protein AgentGene AgentTumor AgentOrchestration Agent

MCP Tool Layer

L3 · Layer 3

Streamable HTTP exposes 8+ tools, JWT authentication, per-dev index isolation. Agents call underlying computing capabilities through standard MCP protocol--tools are hot-pluggable, capabilities are extensible.

8+ MCP ToolsStreamable HTTPJWTper-dev index

Computing Pipeline Layer

L3 · Layer 4

6 pipelines, 30+ AI model-driven--Docker containerized, reproducible delivery. Every computing task scheduled by Agents runs on validated pipelines.

6 pipelines30+ modelsDockerReproducible delivery

CAPABILITIES

What Agents Can Do

Dialog entry points for 6 pipelines--each Agent encapsulates a complete business capability

Protein Structure Prediction

Submit sequences via dialog, Agent auto-calls multi-model prediction, cross-validates confidence

Enzyme Activity Assessment

DLKcat + FoldX + triple-model cross-validation of enzyme activity changes

Gene Editing Plan

Specify target gene, Agent auto-generates gRNA, scans off-targets, optimizes codons

mRNA Design

From antigen sequence to complete mRNA design--one conversation

Precision Oncology

Submit WGS data, Agent auto-annotates -> scores -> medicates -> neoantigens

Interactive Interpretation

Agent doesn't just output files--it interprets results, answers questions, recommends plans

MCP TOOLCHAIN

MCP Toolchain

8+ tools exposed via Streamable HTTP, JWT authentication--Agents call underlying computing through standard protocol

il_query

Asset dynamic knowledge base query

divo_search

Unified hybrid search (BM25 + BGE-M3)

protein_predict

Protein structure prediction scheduling

enzyme_activity

Enzyme activity multi-model cross-validation

gene_edit_design

gRNA design and off-target scanning

mrna_design

mRNA full-module design

variant_annotation

Variant annotation and pathogenicity scoring

coverage_scanner

Pipeline coverage scanning and plan recommendation

COMPARISON

Agent vs Traditional Approach

From "submit task and wait days" to "ask questions and get real-time scheduling"

Agent
InteractionSubmit task -> wait days -> receive file -> interpret yourselfAsk questions -> Agent real-time scheduling -> output results+interpretation+recommendations
Cross-pipeline collaborationManual chaining, each pipeline submitted separatelyAgent auto-decomposes tasks, schedules multi-pipelines, aggregates results
Result interpretationGet numbers and judge yourselfAgent interprets meaning, cross-validates, recommends next steps
Knowledge reuseRepeat background explanation every timeRAG + Investigate Lens auto-retrieves team knowledge

STATUS

Development Status

MCP toolchain is live, dialog engine and domain Agents continuously iterating

MCP Toolchain (8+)Live
Investigate LensLive
Hybrid SearchLive
Dialog Interaction EngineIn Development
Protein Research AgentIn Development
Gene Editing AgentPlanning
Tumor Control AgentPlanning
Private DeploymentPlanning

OPEN SOURCE PLATFORM

Agent Runtime Governance Platform

The above Agent capabilities run on a unified governance platform--AGPL-3.0 open source, community edition free

divo-bio-dev-agent harnessAGPL-3.0

DiVo Agent Platform - Enterprise-grade AI Agent runtime governance platform

sealionking/divo-agent-pub

CROSS-LAYER

Cross-Layer Positioning

L3 Agent layer is the pivot--wrapping L2 models below, delivering capabilities to L4 computing above

L2 · Model

30+ AI model foundation--protein structure, enzyme activity, variant annotation, etc. L3 Agent layer wraps these models, exposing their capabilities as callable tools.

View Model Layer
L3 · Agent

MCP + multi-Agent + RAG--wrapping model capabilities into dialog-based business units, orchestrating tasks, scheduling tools, interpreting results.

L4 · Computing

6 pipelines, Docker containerized, reproducible delivery. Every computing task scheduled by L3 Agents is actually executed and delivered by the L4 computing layer.

View Computing Layer
Model TrainingAgent WrappingComputing Delivery

USER SCENE

Who These Agents Ultimately Serve

B2B2C: Each Agent capability, through dry-computing pipelines, ultimately reaches these end-user scenarios

Experience DiVo Bio Agent Platform

MCP toolchain is live, dialog engine and domain Agents under continuous development. Join us in encapsulating bioinformatics team capabilities into dialog-based interactions.